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Patients must realize that even when taken as suggested, use may well end in addiction, abuse, and misuse; instruct clients never to share their drug with Many others and shield their drug from theft or misuse.CYP450 3A4 Conversation: The concomitant use with CYP450 3A4 inhibitors (or discontinuation of CYP450 3A4 inducers) could bring about a dead